Science-Backed Performance
Every ingredient in F2 has been carefully selected based on peer-reviewed research and clinical studies. We believe in transparency and evidence-based supplementation.
Our Research Philosophy
At F2, we don't just follow trends—we follow the science. Every ingredient in our formula has been selected based on rigorous scientific research and clinical validation.
We believe that effective supplementation should be grounded in evidence, not marketing claims. That's why we've invested in understanding the research behind every component of F2.
Our commitment to research-backed ingredients means you can trust that every scoop of F2 delivers scientifically-proven benefits for your performance and recovery.
Research Standards
Research Articles
Explore some of the scientific studies that support the ingredients in F2. Each article has been carefully selected to demonstrate the evidence-based approach behind our formula.
Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness
Abstract
This study examined whether branched-chain amino acid (BCAA) supplementation before squat exercise could reduce delayed-onset muscle soreness (DOMS) and muscle fatigue in untrained women.
Key Findings
- BCAA supplementation reduced DOMS after squat exercise.
- Decreased muscle fatigue in untrained women.
- Suggests BCAA helps attenuate muscle damage from unaccustomed exercise.
Relevance to F2
Supports the inclusion of BCAAs in F2 formula for reducing soreness and promoting faster recovery post-workout.
Effect of branched-chain amino acid supplementation on the markers of muscle damage and recovery after resistance exercise
Abstract
This study investigated whether BCAA supplementation before and after resistance exercise could attenuate markers of muscle damage and improve recovery of muscle function.
Key Findings
- BCAA supplementation reduced markers of muscle damage.
- Accelerated recovery of muscle function.
- Supports pre- and post-workout supplementation for optimal results.
Relevance to F2
Validates BCAA's role in reducing recovery time and muscle soreness, key for F2’s recovery blend.
Effect of taurine on 3-km running performance in trained middle-distance runners
Abstract
This randomized, double-blind, crossover trial evaluated the effect of acute taurine supplementation on 3-km running performance in trained runners.
Key Findings
- Taurine improved 3-km running performance.
- Likely mediated by enhanced muscle contractility and reduced fatigue.
- Demonstrates acute ergogenic potential.
Relevance to F2
Supports taurine inclusion for improving aerobic and anaerobic performance components in F2.
Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness
Abstract
This study investigated the effects of acute citrulline malate supplementation on anaerobic performance and post-exercise muscle soreness.
Key Findings
- 8g citrulline malate increased repetitions in bench press (~53% more in later sets).
- Reduced post-exercise muscle soreness.
- Indicates improved muscle endurance and recovery.
Relevance to F2
Citrulline malate’s dual role in performance and recovery makes it highly relevant to F2’s multi-function formula.
Citrulline malate enhances cycling time trial performance
Abstract
This randomized controlled trial examined the effect of citrulline malate supplementation on cycling time-trial performance.
Key Findings
- Improved cycling time-trial completion speed.
- Enhanced tolerance to high-intensity exercise.
- Suggests benefits for both aerobic and anaerobic energy systems.
Relevance to F2
Provides strong evidence for citrulline malate’s role in boosting endurance and delaying fatigue for F2 users.
Effects of beta-alanine supplementation on exercise performance: a meta-analysis
Abstract
This meta-analysis reviewed the effects of beta-alanine supplementation on exercise performance, with emphasis on exercise lasting 60–240 seconds.
Key Findings
- Median improvement of 2.85% in performance.
- Greatest benefits for high-intensity exercise lasting 1–4 minutes.
- Supports chronic supplementation for buffering capacity.
Relevance to F2
Beta-alanine helps delay fatigue in short-to-mid duration high-intensity exercise, aligning with F2’s performance goals.
Betaine supplementation improves power performance and body composition
Abstract
This study examined the effects of betaine supplementation on strength, power, and body composition in trained men.
Key Findings
- Increased bench press power output and force production.
- Improved vertical jump performance.
- Enhanced lean mass and reduced fat mass.
Relevance to F2
Betaine’s combined strength, power, and composition benefits make it a strong contributor to F2’s multi-targeted formula.
Creatine supplementation and exercise performance: a meta-analysis
Abstract
A meta-analysis assessing creatine supplementation effects on strength, hypertrophy, and performance in resistance-trained individuals.
Key Findings
- Average increase in maximal strength by 8%.
- Weightlifting performance improved by 14%.
- Effective for high-intensity, short-duration activities.
Relevance to F2
Creatine’s proven strength and power benefits are central to F2’s formula for explosive performance.
Acute Rhodiola rosea intake can improve endurance exercise performance
Abstract
This study assessed the acute effects of Rhodiola rosea supplementation on endurance exercise performance and oxygen uptake.
Key Findings
- Increased time to exhaustion by 24%.
- Improved peak oxygen uptake.
- Reduced perceived exertion.
Relevance to F2
Rhodiola’s adaptogenic and endurance benefits complement F2’s goal of supporting both physical and mental resilience.
Acute branched-chain amino acid supplementation improves recovery of muscle function following resistance exercise
Abstract
This study examined the effects of a single dose of BCAA supplementation (0.087 g/kg body mass) on recovery of muscle function following resistance exercise in resistance-trained individuals.
Key Findings
- BCAA supplementation improved recovery of isometric strength compared to placebo.
- Enhanced jump (CMJ) performance was observed during recovery.
- Participants reported reduced muscle soreness at 24 and 48 hours post-exercise.
Relevance to F2
Highlights BCAA’s ability to accelerate strength recovery and reduce soreness, reinforcing F2’s recovery and performance support role.
Branched-chain amino acid supplementation during intensive training preserves athletic performance and reduces markers of muscle damage
Abstract
This study evaluated the effect of BCAA supplementation during an intensive training program on athletic performance maintenance and muscle damage markers.
Key Findings
- Performance levels were maintained during the intensive training period with BCAAs.
- Markers of muscle damage (e.g., creatine kinase) were significantly reduced.
- Athletes reported lower levels of fatigue.
Relevance to F2
Demonstrates BCAA’s role in sustaining performance and mitigating damage under intense training—critical for F2 users aiming to train harder and recover smarter.
L-Citrulline supplementation improves endothelial function and reduces arterial stiffness in healthy humans
Abstract
This study investigated the effect of 7-day supplementation with L-citrulline (5.6 g/day) on vascular function in middle-aged men, focusing on endothelial function and arterial stiffness.
Key Findings
- L-Citrulline improved flow-mediated dilation (endothelial function).
- There was a significant reduction in systemic arterial stiffness.
- Suggests improved vascular health with supplementation.
Relevance to F2
Supports inclusion of citrulline for its vascular benefits, enhancing blood flow and nutrient delivery—key for F2’s performance and recovery enhancement.
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